There has been a growing recognition that the experience of stress at work has undesirable consequences for the health of employees and their organisations. The European Agency therefore commissioned a report to assess the situation. The report reviews the nature of stress, its causes, extent and management. Focusing on the work environment, it covers its effects both on the individual worker and the organisation, providing a “business case” for stress management. The report suggests a practical approach to tackle stress at work and highlights a number of areas where research is needed to increase our ability to manage work-related stress.