Musculoskeletal disorders (MSDs) are widespread in the hotel, restaurant and catering sector (HORECA). MSDs are work-related impairments of bodily structures such as muscles, joints, tendons, ligaments and nerves. This E-Fact explains why HORECA workers are at risk of developing MSDs. Their jobs, for example, often involve prolonged standing and working in awkward postures. Much of their work is physically demanding, stressful and involves long working hours. Employers need to adapt prevention and intervention strategies to the HORECA sector; workers, who know their work better than anybody, also have an important role to play. A step-by-step guide to risk assessment is explained, as are the European directives relevant to MSDs.