OSHwiki — isocyanates

Type of item
EU & international information
Country
EU
Year of publication
2017

English

Description

This OSHwiki article provides information on the hazards, uses, exposures and risks from isocyanates and outlines prevention strategies at the workplace.
Isocyanates are used in a wide range of industrial products, including paints, glues and resins. They are potent respiratory and skin sensitisers and a common cause of asthma and allergic contact dermatitis (see the OSHwiki article on occupational allergens). A range of other adverse health effects are also associated with isocyanate exposure including cancer. Where isocyanates are used or unintentionally generated, for example when polyurethanes are heated, it is important that workers’ exposures are properly controlled. There are various ways of achieving this, and the way that the isocyanate is used or generated often dictates which control strategy is needed. All exposure control strategies must be reviewed regularly if they are to remain effective, and the article provides information on how to achieve this for isocyanates.

Other data

Provider
Provider name (English)
European Agency for Safety and Health at Work
Provider name (Original)
European Agency for Safety and Health at Work
Tasks covered
Applying Glues or Sealants
Applying Surface Coatings
Construction
Heating or Machining Plastics/Rubber
Heating, Machining, or Welding Metal
Biological hazard
Not applicable
Hazard - physical state
Aerosols
Liquids
Solids
Vapours
Hazard - health effects
Allergens
Skin sensitisers
Asthmagens
Carcinogens
Irritants
Exposure route
Dermal contact
Inhalation
Skin absorption
Substance Description

Toluene diisocyanate,  4,4'-methylenediphenyl diisocyanate,  1,5-naphthylene diisocyanate,  Hexamethylene diisocyanate, Isophorone diisocyanate

CAS Number
26471-62-5
101-68-8
3173-72-6
822-06-0
4098-71-9
EC number
26471-62-5
202-966-0
221-641-4
212-485-8
223-861-6
Prevention measures
Level 1. Elimination of hazards
Level 1. Substitution
Level 2. Technical measures, e.g. local exhaust ventilation
Level 2. Reducing / minimising the risk by organisational measures, e.g. reducing the number of workers exposed
Level 3. Reducing / minimising the risk by personal measures (PPE)
Training / guidance
Hygiene measures
Purpose of the material
General information
Guidance
Target group
Employers
Managers
OSH consultant
Researchers
Safety officers